Hopewell Methodist Church, near Stafford's Landing Ferry on the Altamaha River, is one of the oldest churches in Tattnall County. The church grew out of a prayer meeting conducted by Mary Jane Easterwood Stafford, known then as "Mother" Stafford. Mother Stafford was a devoted Christian woman of great mental and religious strength. She saw the spiritual needs of her neighbors and began prayer services among them. The Ohoopee Circuit pastor soon went to these people and organized a church. During the early 1800s, a great revival spread throughout the southeastern United States. Churches, camp meetings, and conferences were center of revival power. Chapels were built and thousands added to the churches. Hopewell Meeting House was the site of a Quarterly Conference Meeting on November 8 and 9, 1817, with Ezekiel Stafford as the steward.
Much has happened since the beginning of Hopewell UMC. For many years, Hopewell served on the charge with Glennville UMC sharing a pastor and ministry. Recently, Hopewell has become a station church with a pastor of its own. Hopewell UMC celebrated its 200th anniversary in 2017.